Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine

Product Details
Customization: Available
Powder: Yes
Customized: Customized
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  • Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine
  • Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine
  • Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine
  • Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine
  • Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine
  • Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine
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Basic Info.

Model NO.
HB-carmustine
Appearance
White Powder
Sample
Available
Storage
Cool Dry Place
Shelf Life
2 Years
Transport Package
25kg/Drum
Specification
99%
Trademark
Haibo
Origin
China
HS Code
0000
Production Capacity
99999kg/Weeks

Product Description

Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk CarmustineTop Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine
Carmustine is available in a 100-mg vial for IV administrationin the treatment of several types of brain tumors,Hodgkin's and non-Hodgkin's disease, and multiplemyeloma. The agent is also available as an implantablewafer containing 7.7 mg of drug for intracavity implantationin the treatment of glioblastoma multiforme. Cytotoxicity isassociated with cross-linking of DNA and RNA and carbamoylationof glutathione reductase. Cross-resistance isnot seen with other alkylating agents. The agent is very lipidsoluble and easily crosses the blood-brain barrier, achievingconcentrations greater than 50% of those seen in plasma.Metabolism involves both the nonenzymatic formation ofreactive intermediates that may react with glutathione andother thiol-containing proteins, as well as enzymatic reductivedenitrosation and dechlorination. The half-life of theagent in plasma is short (15-20 minutes) because of rapiddecomposition.
Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine
 
 

Function

Myelosuppression is dose limiting and maypresent as thrombocytopenia, leucopenia, or more rarely asanemia. This is generally seen 24 to 48 days after treatment.Pulmonary toxicity occurs rarely at low doses but at highdoses such as those seen during bone marrow transplantmay present as dyspnea, cough, pulmonary infiltrates, andprogress to respiratory failure. This may be seen years afterthe completion of therapy. Other toxicities include nausea,vomiting, pain at the injection site, impotence, sterility,amenorrhea, and infertility. Hepatotoxicity may initiallypresent as elevations in serum transaminase levels. There isalso an increased risk of secondary cancers as is often seenwith the alkylating agents.

Application

1. This product of fat soluble strong, can enter the cerebrospinal fluid, commonly used in the brain primary tumors (such as glioblastoma) and secondary tumor;
2. The treatment of solid tumors, such as gastric cancer and colorectal cancer with fluorouracil in the treatment, combined with methotrexate, cyclophosphamide treatment of bronchial lung cancer;
3. Hodgkin's disease treatment.

Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine
Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine

 

Top Grade Pure Carmustine Powder 99% CAS 154-93-8 Bulk Carmustine
Analysi Specifications
Assay ≥99%
Appearance White powder
Loss on Drying ≤1.0%
Ash ≤1.0%
As ≤2.0ppm
Pb ≤2.0ppm
Insoluble impurity content ≤0.05%
Total Plate Count ≤1000 cfu/g
Yeast &. Mold ≤100 cfu/g
E.Coli Negative
Salmonella Negative
Conclusion
 
Conform USP Standard.
Storage condition
Store in cool & dry place, Keep away from strong light and heat.
Shelf life
2 years when properly stored.
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