Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Dasatinib is a potent atp-competitive inhibitor in biochemical assays with broad-spectrum antiproliferative activities against hematological and solid tumor cell lines. dasatinib was more potent than imatinib at inhibiting nonmutated bcr-abl kinase activity. in addition, the kinase activity of 14 out of 15 different clinically relevant, imatinib-resistant bcr-abl isoforms was successfully inhibited .Dasatinib Monohydrate is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. It is a COVID19-related research product.
Dasatinib monohydrate works by selectively inhibiting the activity of specific tyrosine kinases, such as BCR-ABL, SRC family kinases, and receptor tyrosine kinases. By inhibiting the activity of these kinases, dasatinib monohydrate blocks the signaling pathways that promote the growth and proliferation of cancer cells. This leads o the suppression of tumor growth and helps to control the progression of leukemia.
Item | Test Standard | Testing Result | |
Assay | 99% | Complies | |
Apperence | White Powder | Complies | |
Particle Size | 100% pass 80 mesh | Complies | |
Oder | Characteristic | Complies | |
Taste | Characteristic | Complies | |
Loss on Drying | ≤5.0% | 2.20% | |
Residue on Ignition | ≤0.1% | 0.05% | |
Residual | ≤0.1% | Complies | |
Residual Ethanol | ≤0.5% | Complies | |
Heave Mentals | ≤10ppm | Complies | |
Na | ≤0.1% | <0.1% | |
Pb | ≤3 ppm | Complies | |
Total Plate | <1000CFU/g | Complies | |
Yeast & Mold | <100 CFU /g | Complies | |
E. Coli | Negative | Complies | |
Salmonella | Negative | Complies |