| Customization: | Available |
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| Certification: | RoHS, BRC, ISO, FDA, HACCP |
| Assay Method: | HPLC, UV |
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Diosmin is a naturally occurring flavonoid glycoside that can be isolated from various plant sources or derived from the flavonoid hesperidin. Diosmin is considered to be a vascular-protecting agent used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins. As a flavonoid, diosmin also exhibits anti-inflammatory, free-radical scavenging, and antimutagenic properties.
Diosmin differs molecularly from hesperidin by the presence of a double bond between two carbon atoms in diosmin's central carbon ring. Diosmin can be manufactured by extracting hesperidin from citrus rinds, followed by conversion of hesperidin to diosmin. Diosmin has been used for more than 30 years as a phlebotonic and vascular-protecting agent, and has recently begun to be investigated for other therapeutic purposes, including cancer, premenstrual syndrome, colitis, and diabetes
It was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients, it failed to show sufficient advantages over existing drugs and was discontinued from further development in this application.
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Parameters
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Specs
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Results
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| Appearance | Brown powder | |
| Mesh size | 80 | Compliant |
| Odor | Typical odor | Compliant |
| Detection method | HPLC/UV/TLC | Compliant |
| Ash content | ≤0.5% | ≤0.5% |
| Drying weightlessness | ≤0.5% | ≤0.5% |
| Water content | ≤0.5% | ≤0.5% |
| heavy metal | ≤10ppm | ≤10ppm |
| Arsenic | ≤2.0ppm | ≤2.0ppm |
| Lead | ≤1.0ppm | ≤1.0ppm |
| Cadmium | ≤2.0ppm | ≤2.0ppm |
| Mercury | ≤0.1ppm | ≤0.1ppm |
| Conclusion |
Conform to specification.
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| Storage | Store in a cool and dry place, keep away from direct strong and heat. | |
| Shelf Life | Two years if sealed and store away from direct sun light. | |
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