Supply High Quality Pirfenidone Powder CAS53179-13-8reference Fob Price

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• Purity: >99%
• Appearance: White Powder
• Model NO.: HB-Pirfenidone
• Assay: 99%
• Grade: Food Grade
• Place of Origin: Shaanxi, China
• Package: 1kg/Foil Bag, 25kg/Drum
• Storage: Cool Dry Place
• Transport Package: 1kg/Foil Bag, 25kg/Drum
• Specification: 99%
• Trademark: HAIBO
• Origin: China
• HS Code: 0000
• Production Capacity: 99999kg/Weeks

Product Description

In vitro, pirfenidone can inhibit the proliferation of uterine leiomyoma cells and leiomyoma cells. Pirfenidone inhibits the formation of collagen in TGF-β-1-induced fibroblasts. FGF and TGF-β-1 induced fibroblast proliferation. In the hamster model, pirfenidone, orally, prevents and treat bleomycin-induced pulmonary fibrosis. Pirfenidone can prevent chemically induced rat sclerosing peritonitis and can also be treated with keloid transplantation for nude mice.

Pirrenidone 0.01 1 mg / ml can inhibit the matrix and dose-dependent manner of serum stimulation of uterine fibroids and leiomyoma cell DNA synthesis, the compound without cytotoxicity, the collagen mRNA levels have no effect. Pirfenidone in the hamster pulmonary fibrosis model can reduce the level of collagen I mRNA levels before the disease, reduce lung proline levels and malondialdehyde and lung preservation of amino acid hydroxylase activity.

 

Analysis	Specification	Result	Test method
Physical Description
Appearance	White powder	White powder	Visual
Odor	Characteristic	Characteristic	Organoleptic
Particle size	90% pass 80 mesh	90% pass 80 mesh	80 Mesh Screen
Chemical Tests
Assay (Lutein)	99%	90.15%	HPLC
Loss on drying	5.0% Max	1.82%	5g/105ºC/2hrs
Ash Contents	5.0% Max	1.12%	2g/525ºC/3hrs
Residual Solvents	50.0 ppm, Only Ethanol	<30.0 ppm	/
Heavy metals	5.0 ppm Max	<3.0 ppm	AAS
Lead	3.0 ppm Max	<1.0 ppm	AAS
Arsenic	3.0 ppm Max	<1.0 ppm	AAS
Microbiology Control
Total Bacteria Count	1,000cfu/g Max	<280cfu/g	AOAC
Yeast & Mold	100cfu/g Max	<10cfu/g	AOAC
Coliform	30.0 MPN/g Max	<3.0 MPN/g	AOAC
Conclusion	Complies with the standards.
General Status	Non-GMO, ISO Certificated.