High Quality Atosiban Pharmaceutical Intermediates Atosiban Powder

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: HB-Atosiban
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Appearance: White Powder
• Shelf Life: 2 Years
• Storage: Cool Dry Place
• Packing: Rum, Aluminum Foil Bag
• MOQ: 1kg
• CAS: 90779-69-4
• Sample: Available
• Transport Package: Rum, Aluminum Foil Bag
• Specification: 99%
• Trademark: Haibo
• Origin: Shaanxi, China
• HS Code: 2942000000
• Production Capacity: 50000/Pieces/Years

Product Description

Atosiban Acetate is an inhibitor of the hormones oxytocin and vasopressin. It is used intravenously to halt premature labor.
Atosiban is a synthetic peptide oxytocin antagonist. It binds to membrane bound oxytocin receptors on the myometrium and prevents oxytocin-stimulated increases in inositol triphosphate production. This prevents release of stored calcium from the sarcoplasmic reticulum and subsequent opening of voltage gated calcium channels. This shutdown of cytosolic calcium increase prevents contractions of the uterine muscle, reducing the frequency of contractions and inducing uterine quiescence.

Application: 
1.Atosiban is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/oxytocin receptor antagonist (VOTra).
2.Atosiban inhibits the oxytocin-mediated release of inositol trisphosphatefrom the myometrial cell membrane. 
3.Atosiban is useful in improving the pregnancy outcome of in vitro fertilization-embryo transfer (IVF-ET) in patients with repeated
implantation failure (RIF). The pregnancy rate improved from zero to 43.7%.

 

 

Item	Test Standard		Testing Result
Assay	99%		Complies
Apperence	White Powder		Complies
Particle Size	100% pass 80 mesh		Complies
Oder	Characteristic		Complies
Taste	Characteristic		Complies
Loss on Drying	≤5.0%		2.20%
Residue on Ignition	≤0.1%		0.05%
Residual	≤0.1%		Complies
Residual Ethanol	≤0.5%		Complies
Heave Mentals	≤10ppm		Complies
Na	≤0.1%		<0.1%
Pb	≤3 ppm		Complies
Total Plate	<1000CFU/g		Complies
Yeast & Mold	<100 CFU /g		Complies
E. Coli	Negative		Complies
Salmonella	Negative		Complies