High Quality CAS 220127-57-1 Imatinib Mesylate with Best Price

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: HB-imatinib mesylate
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: ≦96%
• Appearance: White Powder
• Sample: Available
• Storage: Cool Dry Place
• Shelf Life: 2 Years
• Transport Package: 25kg/Drum
• Specification: 99%
• Trademark: Haibo
• Origin: China
• HS Code: 0000
• Production Capacity: 5000kg/Month

Product Description

Imatinib mesylate (also called Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous leukemia.
As an inhibitor, imatinib mesylate appears to have utility in the treatment of a variety of dermatological diseases. Imatinib has been reported to be an effective treatment for FIP1L1Ralpha+ mast cell disease, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans.

Imatinib mesylate in in vitro and in vivo at the cellular level of inhibition of Bcr-Abl tyrosine kinase, can selectively inhibit Bcr-Abl positive cells, Ph chromosome positive chronic myelogenous leukemia and acute lymphoblastic leukemia patients with fresh cell proliferation and induce apoptosis. In addition, imatinib mesylate can also inhibit platelet-derived receptor, stem cell factor (SCF), c-Kit receptor tyrosine kinase, which inhibit  and stem cell factor mediated cell behavior. For the treatment of chronic myelogenous leukemia (CML) blast phase, accelerated phase treatment after failure of chronic phase patients; resection or metastasis of inoperable malignant gastrointestinal stromal tumor (GIST) patients.

Analysi	Specifications
Assay	≥99%
Appearance	White powder
Loss on Drying	≤1.0%
Ash	≤1.0%
As	≤2.0ppm
Pb	≤2.0ppm
Insoluble impurity content	≤0.05%
Total Plate Count	≤1000 cfu/g
Yeast &. Mold	≤100 cfu/g
E.Coli	Negative
Salmonella	Negative
Conclusion	Conform USP Standard.
Storage condition	Store in cool & dry place, Keep away from strong light and heat.
Shelf life	2 years when properly stored.