High Purity 99% Assay Nicorandil Pharmaceuticals Powder with CAS 65141-46-0

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: HB-nicorandil
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: ≦96%
• Appearance: White Powder
• Sample: Available
• Storage: Cool Dry Place
• Shelf Life: 2 Years
• Transport Package: 25kg/Drum
• Specification: 99%
• Trademark: Haibo
• Origin: China
• HS Code: 0000
• Production Capacity: 5000kg/Month

Product Description

Nicorandil is N-(2-hydroxyethyl)-nicotinamide nitrate (ester). It is a white crystalline powder or white needles with a faint, characteristic odour. It is freely soluble in methan ol, ethanol, aceto ne or glacial acetic acid, slightly soluble in chloro form or water, almost insoluble in ether or benzene. Melting point 88.5-93.5 ºC. Acute toxicity LD50 rat (mg/kg): 1200-1300 orally, 800-1000 intravenously.
Function and Application of Nicorandil Powder CAS 65141-46-0

1. Nicorandil is a vasodilator used for the prophylaxis and treatment of angina. This medication widens blood vessels thus increasing the blood and oxygen flow to the heart. It is not currently available in the US.
2. Nicorandil is a nitric oxid e donor and ATP-sensitive potassium channel opener. A study showed that Nicorandil is able to protect against stress-induced cell death in dystrophin-deficient cardiomyocytes and also preserve cardiac function in the mdx mouse heart subjected to ischemia and reperfusion injury.
3. Nicorandil is used for the prevention and treatment of chronic stable angina. It is usually used when angina becomes difficult to control by other drugs and is given as an additional treatment.

Analysi	Specifications
Assay	≥99%
Appearance	White powder
Loss on Drying	≤1.0%
Ash	≤1.0%
As	≤2.0ppm
Pb	≤2.0ppm
Insoluble impurity content	≤0.05%
Total Plate Count	≤1000 cfu/g
Yeast &. Mold	≤100 cfu/g
E.Coli	Negative
Salmonella	Negative
Conclusion	Conform USP Standard.
Storage condition	Store in cool & dry place, Keep away from strong light and heat.
Shelf life	2 years when properly stored.