Good Price and Hot Sale Methotrexate 59-05-2 Chemicals Methotrexate Powder

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: HB-Methotrexate
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Appearance: Yellow Powder
• Shelf Life: 2 Years
• Storage: Cool Dry Place
• Packing: Rum, Aluminum Foil Bag
• MOQ: 100g
• CAS: 59-05-2
• Sample: Available
• Transport Package: Rum, Aluminum Foil Bag
• Specification: 99%
• Trademark: Haibo
• Origin: Shaanxi, China
• HS Code: 2933990099
• Production Capacity: 50000/Pieces/Years

Product Description

Product Description
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate arrests the cell cycle in late G1/S-phase, therefore inhibiting the synthesis of DNA, RNA, thymidylates, and proteins. In the previous cases the inhibition of enzymes involved in purine metabolism, leading to accumulation of adenosine, or the suppression of intercellular adhesion molecule expression by T cells as the main mechanism of action by methotrexate. The compound has been observed to irreversibly inhibit dihydrofolate reductase (DHFR) and thymidylate synthetase (TS). Methotrexate has been shown to modulate inflammation by promoting adenosine release or inhibiting transmethylation reactions. In adherent splenic cells, IL-1 production was decreased by methorexate.

 

Function

1.It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions.
2.It is used for include breast cancer, leukemia, lung cancer, lymphoma, and osteosarcoma.Types of autoimmune diseases
3.It is used for include psoriasis, rheumatoid arthritis, and Crohn's disease.

 

 

 

Item	Test Standard		Testing Result
Assay	99%		Complies
Apperence	Yellow Powder		Complies
Particle Size	100% pass 80 mesh		Complies
Oder	Characteristic		Complies
Taste	Characteristic		Complies
Loss on Drying	≤5.0%		2.20%
Residue on Ignition	≤0.1%		0.05%
Residual	≤0.1%		Complies
Residual Ethanol	≤0.5%		Complies
Heave Mentals	≤10ppm		Complies
Na	≤0.1%		<0.1%
Pb	≤3 ppm		Complies
Total Plate	<1000CFU/g		Complies
Yeast & Mold	<100 CFU /g		Complies
E. Coli	Negative		Complies
Salmonella	Negative		Complies