| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Irsogladine maleate is a selective PDE4 inhibitor that facilitates gap junction intercellular communication through muscarinic acetylcholine receptor binding. It is a potent inhibitor of angiogenesis in wild-type and plasminogen activator-deficient mice.
Function of Irsogladine Maleate
Isoladine maleate has anti-ulcer effect, can strengthen the gastric mucosal epithelial cell binding, enhance the stability of the mucosal itself, to play the role of cell defense, has the effect of increasing gastric mucosal blood flow;Does not affect the basic gastric acid secretion, does not stimulate acid secretion.Isoladine maleate has shown dose-compliant inhibitory or curative effects on experimental gastritis.
Application of Irsogladine Maleate
Inhibition of PDE4 prevents the hydrolysis of cAMP, an important secondary messenger molecule that is heavily involved in signal transduction.
| Item | Test Standard | Testing Result | |
| Assay | 99% | Complies | |
| Apperence | White Powder | Complies | |
| Particle Size | 100% pass 80 mesh | Complies | |
| Oder | Characteristic | Complies | |
| Taste | Characteristic | Complies | |
| Loss on Drying | ≤5.0% | 2.20% | |
| Residue on Ignition | ≤0.1% | 0.05% | |
| Residual | ≤0.1% | Complies | |
| Residual Ethanol | ≤0.5% | Complies | |
| Heave Mentals | ≤10ppm | Complies | |
| Na | ≤0.1% | <0.1% | |
| Pb | ≤3 ppm | Complies | |
| Total Plate | <1000CFU/g | Complies | |
| Yeast & Mold | <100 CFU /g | Complies | |
| E. Coli | Negative | Complies | |
| Salmonella | Negative | Complies | |
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