| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Domperidone is a dopamine blocker and an antidopaminergic reagent.Target: Dopamine ReceptorDomperidone is a useful alternative to metoclopramide for treatment of gastroparesis due to better tolerability. Effectiveness and side-effects from domperidone may be influenced by patient-related factors including polymorphisms in genes encoding drug-metabolizing enzymes, drug transporters, and domperidone targets [1]. Domperidone is a dopamine D(2) receptor antagonist, which has been used as antiemetic agent in human beings. The percentage recovery of domperidone from wastewater was 95.0%. Celiprolol was used as the internal standard to access the percentage extraction of domperidone from wastewater [2]. Domperidone, a dopamine antagonist that does not easily cross the blood-brain barrier, is considered the gold standard for treating gastrointestinal symptoms in patients with Parkinson's disease (PD) because the risk of developing extrapyramidal adverse effects is considered minimal.
Domperidone is a benzimidazole compound that has strong stomach-stimulating and antiemetic effects, can strengthen the lower esophageal sphincter tension, prevent gastric-esophageal reflux, enhance gastric motility, promote gastric emptying, and coordinate the stomach with the twelve-finger Intestinal exercise, inhibition of nausea, vomiting, and effective prevention of bile reflux, does not affect the secretion of gastric juice.
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Analysis
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Specification
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Result
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Test method
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Physical Description
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Appearance
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White Powder
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White Powder |
Visual
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Odor
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Characteristic
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Characteristic
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Organoleptic
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Particle size
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90% pass 80 mesh
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90% pass 80 mesh
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80 Mesh Screen
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Chemical Tests
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Assay (Lutein)
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99%
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90.15%
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HPLC
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Loss on drying
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5.0% Max
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1.82%
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5g/105ºC/2hrs
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Ash Contents
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5.0% Max
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1.12%
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2g/525ºC/3hrs
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Residual Solvents
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50.0 ppm, Only Ethanol
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<30.0 ppm
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/
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Heavy metals
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5.0 ppm Max
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<3.0 ppm
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AAS
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Lead
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3.0 ppm Max
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<1.0 ppm
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AAS
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Arsenic
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3.0 ppm Max
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<1.0 ppm
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AAS
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Microbiology Control
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Total Bacteria Count
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1,000cfu/g Max
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<280cfu/g
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AOAC
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Yeast & Mold
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100cfu/g Max
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<10cfu/g
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AOAC
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Coliform
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30.0 MPN/g Max
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<3.0 MPN/g
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AOAC
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Conclusion
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Complies with the standards.
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General Status
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Non-GMO, ISO Certificated.
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