Pharmaceutical Chemical Factory Supply High Quality Ambrisentan CAS#177036-94-1

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: HB-ambrisentan
• Appearance: White Powder
• Sample: Available
• Storage: Cool Dry Place
• Shelf Life: 2 Years
• Transport Package: 25kg/Drum
• Specification: 99%
• Trademark: Haibo
• Origin: China
• HS Code: 0000
• Production Capacity: 5000kg/Month

Product Description

The peptide endothelin constricts muscles in blood vessels, increasing blood pressure. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA). Ambrisentan significantly improved exercise capacity (6-minute walk distance) compared with placebo in two double-blind, multicenter trials (ARIES-1 and ARIES-2).Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), and designated an orphan drug, for the treatment of pulmonary hypertension.

The efficacy and effect of Anlisentan tablet is mainly suitable for the treatment of pulmonary hypertension patients with WHO grade symptoms (WHO group 1), to improve exercise ability and delay clinical deterioration. Studies supporting the effectiveness of Antesentan mainly included patients with idiopathic or hereditary PAH(64%) or connective tissue disease-associated PAH(32%) etiological characteristics.

Analysi	Specifications
Assay	≥99%
Appearance	White powder
Loss on Drying	≤1.0%
Ash	≤1.0%
As	≤2.0ppm
Pb	≤2.0ppm
Insoluble impurity content	≤0.05%
Total Plate Count	≤1000 cfu/g
Yeast &. Mold	≤100 cfu/g
E.Coli	Negative
Salmonella	Negative
Conclusion	Conform USP Standard.
Storage condition	Store in cool & dry place, Keep away from strong light and heat.
Shelf life	2 years when properly stored.