| Customization: | Available |
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| Certification: | RoHS, BRC, ISO, FDA, HACCP |
| Assay Method: | HPLC, UV |
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Diacerein, molecular formula C19H12O8, is an important inhibitor of IL-1 in osteoarthritis. Diacerein, also known as diacetyldihydroanthracene carboxylic acid, 1,8-diacetyl-3-carboxyanthraquinone, dacerein, and ambitine, is a new interleukin (IL)-1 inhibitor , The chemical name is diacetyl rhein, which is an anthraquinone compound. This product can induce cartilage formation, has analgesic, anti-inflammatory and antipyretic effects, and can also significantly improve the joint function of patients with osteoarthritis, delay the course of the disease, and relieve pain. , to improve the quality of life of patients, with good safety, mainly used in clinical treatment of osteoarthritis (OA) and play an antibacterial effect.
Function
1.Diacerein has the role of delaying the deterioration processes of osteoarthritis.
2.Diacerein can exert effects of anti-inflammatory and anti-febrile by combining with oxygen free radical and inactivating it.
3.Diacerein could form water-soluble chelating(EGTA and EDTA-Cu) of resisting rheumatism with calcium and copperions.
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Parameters
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Specs
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Results
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| Appearance | Yellow powder | White or off white powder |
| melting point | 258~263ºC | 258~263ºC |
| content(HPLC) | ≥99% | ≥99% |
| Drying weightlessness | ≤0.5% | ≤0.5% |
| Water content | ≤0.5% | ≤0.5% |
| heavy metal | ≤10ppm | ≤10ppm |
| Arsenic | ≤2.0ppm | ≤2.0ppm |
| Lead | ≤1.0ppm | ≤1.0ppm |
| Cadmium | ≤2.0ppm | ≤2.0ppm |
| Mercury | ≤0.1ppm | ≤0.1ppm |
| Conclusion |
Conform to specification.
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| Storage | Store in a cool and dry place, keep away from direct strong and heat. | |
| Shelf Life | Two years if sealed and store away from direct sun light. | |
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