| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Tofacitinib citrate is a king of drugs developed by the US pharmaceutical company for treating rheumatoid arthritis, for the treatment of methotrexate inadequate response or intolerance to severe active rheumatoid arthritis (RA) in adult patients. Tofacitinib citrate is approved for the treatment of methotrexate inadequate response or intolerance to severe active rheumatoid joints arthritis (RA) in adult patients.
Tofacitinib citrate is an oral drug used for treating rheumatoid arthritis. It belongs to a class of drugs called Janus kinase (JAK) inhibitors. JAKs are enzymes (proteins) that regulate chemical signaling pathways that control biologic processes such as blood formation and the immune response that causes the pain, tenderness and swelling of inflammation. JAKs are found in many cells, especially stem cells in bones and joints. Inhibition of JAKs by tofacitinib prevents inflammation and tissue destruction that is associated with the inflammation of rheumatoid arthritis.
| Analysi | Specifications | |
| Assay | ≥99% | |
| Appearance | White | |
| Loss on Drying | ≤1.0% | |
| Ash | ≤1.0% | |
| As | ≤2.0ppm | |
| Pb | ≤2.0ppm | |
| Insoluble impurity content | ≤0.05% | |
| Total Plate Count | ≤1000 cfu/g | |
| Yeast &. Mold | ≤100 cfu/g | |
| E.Coli | Negative | |
| Salmonella | Negative | |
| Conclusion |
Conform USP Standard.
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| Storage condition |
Store in cool & dry place, Keep away from strong light and heat.
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| Shelf life |
2 years when properly stored.
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