| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Product Name:Fosfomycin Tromethamine
CAS:78964-85-9
Fosfomycin tromethamine is a phosphonic acidepoxide derivative, which expands the therapeutic utility of tromethamine salt because its water solubility increased enough to allow oral administration.Fosfomycin tromethamine is a bactericidal phosphonic acid derivative which acts primarily by inhibiting bacterial cell wall (peptidoglycan) synthesis. It has antibacterial activity against many pathogenic and opportunistic Gram-positive and Gram-negative bacteria isolated from patients with lower urinary tract infections (UTI). According to conventional in vitro susceptibility tests, fosfomycin has good activity against Escherichia coli, Staphylococcus aureus, and Serratia, Klebsiella, Citrobacter, Enterococcus and Enterobacter spp. Minimum inhibitory concentrations active against 90% of isolates (MIC90 values) for some other important pathogens are relatively high, but are well within the urinary concentrations of fosfomycin achieved during treatment with the drug.
| Analysi | Specifications | Result |
| Assay | ≥99% | 99.2% |
| Appearance | White powder | Complies |
| Loss on Drying | ≤1.0% | 0.04% |
| Ash | ≤1.0% | 0.1% |
| As | ≤2.0ppm | <2.0ppm |
| Pb | ≤2.0ppm | <2.0ppm |
| Insoluble impurity content | ≤0.05% | Complies |
| Total Plate Count | ≤1000 cfu/g | Complies |
| Yeast &. Mold | ≤100 cfu/g | Complies |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
| Conclusion |
Conform USP Standard.
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| Storage condition |
Store in cool & dry place, Keep away from strong light and heat.
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| Shelf life |
2 years when properly stored.
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