Factory Supply High Quality API High Purity Losartan CAS 114798-26-4

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: HB-Losartan
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: 99%
• Test: HPLC
• Packing: Rum, Aluminum Foil Bag
• MOQ: 1kg
• Grade: Food Grade
• Function: Pharmaceutical Intermediate
• Transport Package: Aluminum Foil Bag, Carton Box
• Specification: 99%
• Trademark: Haibo
• Origin: Shaanxi, China
• HS Code: 00000000
• Production Capacity: 5000000/Year

Product Description

Losartan is an angiotensin II receptor (AT1) blocking agent. There are two subtypes of angiotensin II receptors, AT1 and AT2. AT1 receptors are mainly distributed in vascular smooth muscle and cardiac tissue, while AT2 receptors are mainly distributed in the adrenal medulla and other sites. Blocking AT1 receptors can reduce peripheral resistance and blood volume, resulting in lower blood pressure, with an antihypertensive effect similar to that of enalapril.

Losartan is an AT1 receptor antagonist of angiotensin II. It can block the effects of endogenous and exogenous angiotensin II on promoting vasoconstriction and aldosterone release; it does not affect the functions of other hormone receptors or important ion channels in the cardiovascular system, and does not inhibit the degradation of bradykinin Angiotensin-converting enzyme does not affect the metabolic process of angiotensin and bradykinin. For the treatment of essential hypertension.

 

Item	Specification
Type/Grade	XJ-101
(dry basis)≥%	99.8
BET Surface Area m²/g	180-210
Loss On Heating 105ºC2h%	4.0-8.0
Lgnition loss at 1000ºC%≤	3.0-7.0
PH Value	6.0-7.5
DBP absorption Value cm³/g	2.4-2.8
Na2SiO4%≤	1.0
Fe(mg/kg)≤	200
Cu content(mg/kg)	30
Mn(mg/kg)	50
Average Particle Size(D50)μm	13-16
Sieve residue(45μm)%	0.5