High Quality Pharmaceutical Raw Material Tobramycin Powder CAS 32986-56-4 Tobramycin

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: HB-Tobramycin
• Test: HPLC
• Packing: Rum, Aluminum Foil Bag
• MOQ: 1kg
• Grade: Pharmaceutical Grade
• Shelf Life: 2 Years
• Storage: Cool Dry Place
• Color: White
• Transport Package: 1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
• Specification: 99%
• Trademark: Haibo
• Origin: Shaanxi, China
• HS Code: 3006930000
• Production Capacity: 5000000/Year

Product Description

Tobramycin is one component (factor 6) of a mixture produced by fermentation of Streptomyces tenebrari us. Lacking the C-3′ hydroxyl group, it is not a substrate for APH(3′)-1 and APH(3′)-II and so has an intrinsically broader spectrum . It is a substrate, however, for adenylation at C-2′ by ANT (2′) and acetylation at C-3 by AAC(3)-I and AAC(3)-II and at C-2′ by AAC(2′).

Function 
Tobramycin is an aminoglycoside antibiotic used to treat various types of bacterial infections, particularly Gram-negative infections. Tobramycin, an aminoglycoside antibiotic, has almost the same antibacterial spectrum as Gentamycin, but enjoys lower nephrotoxicity and otoxicity than Gentamycin. It has high antibacterial activity in Gram-negative bacteria, especially against Pseudomonas  areuginosa. Besides, it exerts synergic effect in combination with Penicillins or Cephalosporins.

Tobramycin is highly active with respect to Gram-negative microorganisms (blue-pus bacillus and gastric bacilli, rabbit fever, serratia, providencia, enterobacteria, proteus, salmonella, shigella), as well as Gram-positive microorganisms (staphylococci, including those resistant to penicillin and some cephalosporins), and a few strains of streptococci. It is used for severe bacterial infections: peritonitis, sepsis, meningitis, osteomyelitis, endocarditis, pneumonia, pleural empyema, pulmonary abscess, purulent skin infections and soft tissue infections, and infections of the urinary tract caused by microorganisms that are sensitive to the drug. Synonyms of this drug are nebicine, obracine, and others.

tems	Standards	Results
Physical Analysis
Description	White Powder	Complies
Assay	99%	99.6%
Mesh Size	100 % pass 80 mesh	Complies
Ash	≤ 5.0%	2.85%
Loss on Drying	≤ 5.0%	2.65%
Chemical Analysis
Heavy Metal	≤ 10.0 mg/kg	Complies
Pb	≤ 2.0 mg/kg	Complies
As	≤ 1.0 mg/kg	Complies
Hg	≤ 0.1mg/kg	Complies
Microbiological Analysis
Residue of Pesticide	Negative	Negative
Total Plate Count	≤ 1000cfu/g	Complies
Yeast&Mold	≤ 100cfu/g	Complies
E.coil	Negative	Negative
Salmonella	Negative	Negative