Supply High Purity API Powder CAS 1400-61-9 Nystatin

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: HB-nystatin
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: ≦96%
• Appearance: Yellow Powder
• Sample: Available
• Storage: Cool Dry Place
• Shelf Life: 2 Years
• Transport Package: 25kg/Drum
• Specification: 99%
• Trademark: Haibo
• Origin: China
• HS Code: 0000
• Production Capacity: 5000kg/Month

Product Description

Nystatin is a polyene antifungal drug to which many molds and yeast infections are sensitive, including Candida.

Cutaneous, vaginal, mucosal and esophageal Candida infections usually respond well to treatment with nystatin.

Like amphotericin B and natamycin, nystatin binds to ergosterol, a major component of the fungal cell membrane. When present in sufficient concentrations, it forms pores in the membrane that lead to K+ leakage and death of the fungus.

Function:

1). Nystatin is often used as prophylaxis in patients who are at risk for fungal infections.

2). It is prescribed in units, with doses varying from 100,000 (for oral infections) to 1 million (for intestinal ones). As it is not absorbed from the gut, it is safe for oral use and does not have problems of drug interactions.

3). It is also used in cellular biology as an inhibitor of the lipid raft-caveolae endocytosis pathway on mammalian cells, at concentrations around 3 µg/mL.

4). In certain cases, nystatin has been used to prevent the spread of mold on objects such as works of art. For example, it was applied to wood panel paintings damaged as a result of the Arno River Flood of 1966 in Florence, Italy.

5). Nystatin is also used as a tool by scientists performing "perforated" patch-clamp electrophysiologic recordings of cells. When loaded in the recording pipette, it allows for measurement of electrical currents without washing out the intracellular contents, because it forms pores in the cell membrane that are permeable to only monovalent ions.

 

Analysi	Specifications
Assay	≥99%
Appearance	yellow powder
Loss on Drying	≤1.0%
Ash	≤1.0%
As	≤2.0ppm
Pb	≤2.0ppm
Insoluble impurity content	≤0.05%
Total Plate Count	≤1000 cfu/g
Yeast &. Mold	≤100 cfu/g
E.Coli	Negative
Salmonella	Negative
Conclusion	Conform USP Standard.
Storage condition	Store in cool & dry place, Keep away from strong light and heat.
Shelf life	2 years when properly stored.