| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Tiotropium bromide, also known as tautropine bromide, is a new type of bronchodilator, which was successfully developed by the Dutch company Boehringer Ingelheim. It is a long-acting anticholinergic drug that has a selective inhibitory effect on M3 receptors and has blood The drug concentration is maintained for a long time and side effects are small. The efficacy of tiotropium bromide for the treatment of chronic obstructive pulmonary disease (COPD) is equivalent to ipratropium bromide, but its advantage is that it only needs to be administered once a day, while the latter It takes 4 doses a day. Recent studies have shown that long-acting β2 adrenergic receptor agonists can also effectively expand the bronchus compared with short-acting ones.
Function
Tiotropium is a muscarinic receptor antagonist, often referred to as an antimuscarinic or anticholinergic agent. Although it does not display selectivity for specific muscarinic receptors, on topical application it acts mainly on M3 muscarinic receptorslocated on smooth muscle cells and submucosal glands not to produce smooth muscle contration and mucus secretion, thus producing a bronchodilatory effect.
| Analysi | Specifications | |
| Assay | ≥99% | |
| Appearance | White powder | |
| Loss on Drying | ≤1.0% | |
| Ash | ≤1.0% | |
| As | ≤2.0ppm | |
| Pb | ≤2.0ppm | |
| Insoluble impurity content | ≤0.05% | |
| Total Plate Count | ≤1000 cfu/g | |
| Yeast &. Mold | ≤100 cfu/g | |
| E.Coli | Negative | |
| Salmonella | Negative | |
| Conclusion |
Conform USP Standard.
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| Storage condition |
Store in cool & dry place, Keep away from strong light and heat.
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| Shelf life |
2 years when properly stored.
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