Supply Cosmetic Raw Material Skin Whitening 99% Monobenzone Powder

• Customization: Available
• CAS No.: 103-16-2
• Formula: C20h20o3
• Model NO.: HB-Monobenzone Powder
• Type: Pharmaceutical Intermediates
• Appearance: White Powder
• Quality: Refined
• Colour: White
• MOQ: 1kg
• Single Gross Weight: 1.5kg
• Sample: Avaliable
• Single Package Size: 40X20X40 Cm
• Grade: Food Grade
• Transport Package: Package
• Specification: 99%
• Trademark: HaiBo
• Origin: Xi′an
• HS Code: 0000
• Production Capacity: 1000000

Product Description

           Monobenzone can decompose melanin in the skin, and prevent the formation of melanin in the skin, used for the treatment of hyperpigmentation, such as various spots, age spots, melanoma. In addition as intermediates in organic synthesis.

Function:

The topical application of monobenzone in animals increases the excretion of melanin from melanocytes. The same
action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause
destruction of melanocytes and permanent depigmentation.

The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo; the
epidermis is normal except for the absence of identifiable melanocytes. Therefore, monobenzone is used as a topical
medicine to permanently depigment normal skin surrounding vitiliginous lesions only in patients with disseminated
(greater than 50 percent of body surface area) idiopathic vitiligo. Monobenzone is also being considered for the
treatment of Melanoma.

Monobenzone is also used to derive dyes for fiber dyeing and is used in the rubber industry.

Application:
  (1)Monobenzone is the monobenzyl  of . Monobenzone occurs as a white, almost tasteless
crystalline powder, soluble in alcohol and practically insoluble in water.
(2)Monobenzone is a compound used as a topical drug for medical depigmentation. The topical application of
monobenzone in animals decreases the excretion of melanin from melanocytes. The same action is thought to be
responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes
thus, bringing about permanent dipigmentation in vitiligo patients.
(3)Monobenzone is the monobenzyl of . Monobenzone powder can be compounded to make a
depigmenting cream. It is used to whiten patchy skin and create and even skin tone that is pale and smooth.
(4)Monobenzone USP, is a strong depigmentation agent, used to treat the patients suffering from vitiligo.
(5)Monobenzone 20% ointment is used specifically for vitiligo.
 

Items	Specifications	Results
Appearance	white powder	Complies
Identification	Positive	Complies
Assay	98	98.5%
Ash	≤5.0%	2.55%
Loss on drying	≤5.0%	1.20%
Ignition residue	≤2.0%	0.25%
Heavy metals	≤10ppm	Complies
Pb	≤2.0ppm	Complies
As	≤2.0ppm	Complies
Odor	Characteristic	Complies
Particle size	100%through 80 mesh	Complies
Microbioiogical:
Total of bacteria	≤1000cfu/g	100cfu/g
Fungi	≤100cfu/g	Complies
Salmgosella	Negative	Complies
Coli	Negative	Complies
Conclusion	Conform with USP/FCC/E302 specification
Storage condition	Store in cool & dry place, Do not freeze. Keep away from strong light and heat.
Shelf life	2 years when properly stored